![]() Safety and efficacy of Testosterone Gel 1% in men with "age-related hypogonadism" (also referred to as "late-onset hypogonadism") have not been established.These men have low testosterone serum concentrations, but have gonadotropins in the normal or low range. Hypogonadotropic hypogonadism (congenital or acquired): gonadotropin or luteinizing hormone-releasing hormone (LHRH) deficiency or pituitary-hypothalamic injury from tumors, trauma, or radiation.These men usually have low serum testosterone concentrations and gonadotropins (follicle-stimulating hormone, luteinizing hormone ) above the normal range. Primary hypogonadism (congenital or acquired): testicular failure due to conditions such as cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter's syndrome, chemotherapy, or toxic damage from alcohol or heavy metals. ![]() Testosterone Gel 1% is indicated for replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone: Indications and Usage for Testosterone Gel
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